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ASNO Neuro-Oncology 2024 Conference in Singapore: Insights into Neuropathology

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ASNO Neuro-Oncology 2024 Conference in Singapore: Insights into Neuropathology From August 14-18, 2024, the 19th Asian Society for Neuro-Oncology (ASNO) annual meeting was held in Singapore, bringing together top specialists from around the world to discuss the latest research in neuro-oncology. Author Harutyun Papoyan Pathologist From HistoGen lab, we had a pathologist Harutyun Papoyan representing us at this prestigious event, providing an excellent platform for sharing knowledge on the diagnosis and management of brain tumors. One of the most impactful sessions was a full day dedicated to neuropathology, where leading experts presented in-depth case studies on gliomas and meningiomas. These presentations highlighted the diagnostic complexities of these tumors, focusing on differential diagnosis through molecular profiling techniques. Gliomas, often challenging to diagnose, were the subject of several detailed case presentations. Speakers presented how novel genetic markers are aiding in distinguishing these tumors from other central nervous system lesions. For meningiomas, a range of clinical cases was shared, covering various grades and the diagnostic challenges they pose, particularly in distinguishing benign forms from more aggressive variants. Our lab’s pathologist had the opportunity to meet with prominent neuropathologists from Japan, India, Hong Kong, and Singapore. These interactions fostered discussions on clinical cases, diagnostics, and emerging trends in the field, paving the way for potential research collaborations. The knowledge and experience gained at the ASNO 2024 conference have enriched our lab’s approach to neuro-oncology research, particularly in understanding the subtleties of diagnosing gliomas and meningiomas. We look forward to incorporating these insights into our ongoing work and building on the connections made during the event. We would like to extend our heartfelt thanks to Ibrahim Qaddoumi, MD, MS and St. Jude hospital for the opportunity to participate in this incredible event and contribute to the future of neuropathology. The breast biopsy The breast biopsy

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Կրծքագեղձի բիոպսիա, Биопсия молочной железы

The breast biopsy

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  The breast biopsy </h1 > The breast biopsy is a medical manipulation procedure where a small sample is taken from breast tissue, which is then examined under the microscope by a pathologist. author Voskehat Mkrtumyan Pathologist The biopsy is performed when a lesion is suspected or detected either on sonography or mammography and it is necessary to find out whether the lesion is benign or malignant or else there might be an inflammatory process. After the microscopic examination of the sample the pathologist can tell what kind of lesion it is. If it is a cancer, then a further immunohistochemical examination is needed to distinguish the subtype of the tumor. During that examination the amount of hormonal receptors or Her2neu status and Ki67 cell division activity in tumor cells are evaluated. Molecular subtype is needed for further neoadjuvant, hormonal or targeted chemotherapies, sometimes also the combination of all three. Sometimes Her2neu status is evaluated as equivocal. In those cases another examination which is called FISH testing is needed, which evaluates if mutation is present in the Her2neu gene. Positive Her2neu status allows the clinician to perform neoadjuvant hormonal chemotherapy with a drug called Herceptin. It is important to mention that after biopsy benign lesions do not become malignant and malignant ones cannot become more aggressive and the biopsy is necessary and irreplaceable if there are medical indications. After the procedure hematomas, bleeding or pain can follow. Patients often wonder if the process is painful. The ones who have gone through the procedure say that what they felt was more of discomfort rather than pain, although it is a subjective sensation and can be varied. Moreover, it is essential to mention that due to modern medicine achievements, breast cancer can be treated in most cases if detected in time. For a probable early detection monthly self-observation is needed, however, one should consider that not all the lesions can be palpated, besides, preventive measures should be taken: sonography (if the patient is 30-40 years old) or mammography (if the patient is 40 years old or above). Կրծքագեղձի բիոպսիա Կրծքագեղձի բիոպսիա Նևուսներ (խալեր) Նևուսներ (խալեր) Մոլեկուլային պաթոլոգիա Մոլեկուլային պաթոլոգիա Պապ թեստ Պապ թեստ

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