Molecular pathology

Molecular pathology

Molecular pathology is the study of changes in DNA in human samples (tissues/cells). It is used to diagnose cancer, determine prognosis and treatment options, and monitor response to therapy.

Molecular pathologists are experts who use laboratory methods to analyze tissue or cytology samples from patients with cancer or other diseases. They may also develop new tests for detecting genetic mutations that cause disease, which can help doctors make better-informed decisions about treatment options for patients with certain types of cancers that have a high risk of recurrence after surgery radiation therapy or chemotherapy.

Molecular pathology is a tool that enables the identification of cancer cells and their origin. Our experienced laboratory scientists conduct molecular testings using FISH, qPCR and NGS methods to help you determine the nature and mutational profile of tumor. HistoGen laboratory offers wide range of molecular pathological testing. We perform tests in human cancer tissues and cytology specimens using FISH, qPCR and NGS methods. Our professional team provides deep knowledge about different pathways and mechanisms that can cause cancer. We offer molecular tests to identify the actual molecular profile of a disease. It can be used to determine what kind of treatment plan is selected, identify biomarkers for patients and stratify them into groups that need targeted therapy. We also perform analysis to know the statuses of MMR/MSI, ALK, HER2neu, PD-L1 (SP263), p16, β-catenin by automated immunohistochemistry using validated monoclonal antibodies (MAB’s) and ASSAY’s . We also offer a wide range of diagnostic test kits and reagents which can be used to detect and differentiate various kinds of cancers.

Our products have been tested in accordance with international standards and regulations, such as FDA and CE certification. HistoGen is the leading pathology lab in Armenia which continues implementation of diagnostic kits for cancer research and clinical use. We have a team of skilled pathologists who lead the development of our company’s diagnostic tests. We offer high-quality cancer diagnosis services to our customers based on scientific research and innovation. Currently, our laboratory is equipped with IVD reagents for the detection of mutations in the following genes – EGFR, KRAS, NRAS, HRAS, BRAF, IDH1/2, PIK3CA, ERBB2, c-MYC, n-MYC, MDM2, ALK, ROS1, MET, RET, NTRK1, NTRK2, NTRK3, EWSR, SS18, Bcl2, Bcl6, PTEN, CDKN2A, 1p/19q. The reagent kits also allow for spot testing on tumors of certain organs, such as breast cancer, lung cancer, brain gliomas/ependymomas, soft tissue tumors, lymphomas, cervical cancer, endometrial cancer, thyroid cancer, colon cancer, stomach cancer, ovarian cancer, prostate cancer, melanoma and other skin tumors. We are constantly developing our tests, offering new and improved versions.

Our company cooperates with the best pathology laboratories abroad. Our team is highly qualified and experienced in this field to provide the best service to our clients.

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